Postdoctoral Researcher (f/m/d) on grid cell coding in preclinical Alzheimer’s Disease

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    Chair for Translational Neurodegeneration, DZNE
    Biological sciences
    Computer science
    First Stage Researcher (R1)
    Recognised Researcher (R2)
    Established Researcher (R3)
    Leading Researcher (R4)
    26/05/2020 23:59 - Europe/Brussels
    Germany › Magdeburg

The German Center for Neurodegenerative Diseases (DZNE, https://www.dzne.de/en/) is a unique non-university research center which is dedicated to the subject dementia and all its areas, as well as other neurodegenerative diseases. The center encompasses the full spectrum of fundamental research through population sciences to health care research. The DZNE stands for excellence in research and science management, translation of scientific results into practice, interdisciplinarity and internationalization. It is a research center within the Helmholtz Organization of German research centers. With over 1000 employees from 60 nations, spread over 10 sites, the DZNE is one of the leading national and international research centers in its research field.

The DZNE in Magdeburg is looking for a

Postdoctoral Researcher (f/m/d) on grid cell coding in preclinical Alzheimer’s Disease
Code 4042/2020/3

One Postdoc position is available in the Aging & Cognition research group (http://www.wolberslab.net/), headed by Prof. Thomas Wolbers. This project – is funded by the CoEN initiative (https://www.coen.org/) – is an exciting interdisciplinary collaboration with the groups of Mark Brandon (McGill University, https://brandonlab.weebly.com/) and Ila Fiete (MIT, https://fietelab.mit.edu/). The overall aim is to characterise how computations in the entorhinal grid cell system are affected in early Alzheimer’s disease (AD). Using a combination of cutting‐edge interactive virtual reality (VR) and ultra-high field neuroimaging, you will develop innovative VR paradigms and use computational models to generate novel predictions for altered spatial coding in preclinical AD. Importantly, the successful candidate will closely interact with the collaborating labs and will also be encouraged to work on translating the experimental findings into clinical tools.

In addition to hosting research dedicated 3T and 7T MRI scanners, the Magdeburg site of the DZNE, where the group is based, provides access to EEG, MEG, TMS and eye tracking systems. Furthermore, the Aging and Cognition lab has a range of cutting-edge VR setups (http://www.wolberslab.net/facilities.html), and it entertains a range of international collaborations. Finally, Magdeburg offers a unique intellectual environment, because spatial navigation is a core theme investigated across several animal and human research groups.

What we are looking for
For this position, excellent statistical and programming skills (e.g. in Python, R, Matlab) and strong interest in dementia and computational modelling are essential. A background in neuroimaging is a plus. You will be thorough, efficient, a good communicator, and enjoy working as part of an international and dynamic team. For further information about this unique opportunity, please email Thomas Wolbers (thomas.wolbers@dzne.de). To learn more about our research, please visit our website (http://www.wolberslab.net/) and follow us on Twitter.

What we offer
The position is available initially for 2 years, with a strong intention to be extended for a considerably longer time. The position is available from 01 September 2020, but applications will be considered until the position is filled. You will obtain special skills and knowledge for your scientific qualification. Interested candidates should submit their applications including a CV, a letter stating research interests and two of the usual references.

The DZNE is an equal opportunity employer. It especially welcomes and encourages disabled individuals to apply. To submit your application please visit: https://jobs.dzne.de/en/jobs/40528/form

Further reading

Lester, A., Moffat, S., Wiener, J.M., Barnes, C.A., & Wolbers, T. (2017). The Aging Navigational System. Neuron, 95(5), 1019–1035.

Stangl, M., Achtzehn, J., Huber, K., Dietrich, C., Tempelmann, C., & Wolbers, T. (2018). Compromised grid-cell-like representations in old age as a key mechanism to explain age-related navigational deficits. Current Biology, 28(7), 1108-1115.

Stangl, M., Kanitscheider, I., Riemer, M., Fiete, I.R. & Wolbers, T. (2020). Sources of path integration error in young and aging humans. Nature Communications.

Offer Requirements


Professional Certification

Work location(s)
1 position(s) available at
Chair for Translational Neurodegeneration, DZNE

EURAXESS offer ID: 509883
Posting organisation offer ID: 723877


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